Blood Diseases MCQs

Chediak- Higashi syndrome is inherited as
A. X-linked dominant trait
B. Autosomal dominant
C. Autosomal recessive
D. X-linked recessive
Which of the following blood disease has a racial predilection ?
A. Purpura
B. Hemophilia
C. Polycythemia
D. Thalassemia
In Radionucide imaging the most useful radio pharmaceutical for skeletal imaging is:
A. Gallium 67 (67 Ga)
B. Technetium-99m (99m Tc-Sc)
C. Technetium-99m (99m Tc)
D. Technetium-99m linked to Methylene disphosonate (99m Tc-MDP)
The most striking haematological finding in agranulocytosis is:
A. Decreased absolute neutrophil count
B. Increased absolute eosinophil count
C. Decreased absolute basophil count
D. Increased absolute monocyte count
Deficiency of all the three components of coagulation factor VIII result in:
A. Von willebrand’s disease
B. Haemophilia- A
C. Parahemophilia
D. Haemophilia – B
Which of the following is not true about thalassemia:
A. Increased in number of globulin chain
B. There is erythrocyte fragility and hemolysis
C. Hypochromic microcytic anaemia is present
D. There is severe anaemia and thrombocytopenia
A hair on end appearance of the skull is seen in all of the following except
A. Thalassemia
B. Sickle anemia
C. Cooley’s anaemia
D. Pagets disease
Hemophilia is associated with:
A. Normal bleeding time normal clotting time
B. Normal bleeding time prolonged clotting time
C. Prolonged bleeding time normal clotting time
D. Prolonged bleeding time prolonged clotting time
One of the following syndrome is characterized by an esophageal web with resulting dysphagia, atrophic changes in the mucous membranes of the mouth and a hypochromic microcytic anemia:
A. Marfan’s syndrome
B. Plummer-vinson
C. Meckels syndrome
D. sjogren’s syndrome
Oral manifestations of infectious mononucleosis is most commonly:
A. Bluish red spots opposite maxillary molar
B. Pseudomembrane on gingiva
C. Pinpoint petechiae on the palate
D. Gingival hyperplasia
Chemotherapy can be successful during treatment of:
A. Ameloblastoma
B. Leukemia
C. Fibrosarcoma
D. Basal cell carcinoma
Precancerous potential in plummer-vinson’s syndrome may be due to change in the epithelium like:
A. Atrophy
B. Hypertrophy
C. Acanthosis
D. All of the above
Which of the following is the most serious and life threatening blood dyscrasias caused with a drug:
A. Aplastic anemia
B. Megaloblastic anemia
C. Thrombocytopenia
D. Hemolytic anemia
For extraction in a leukemic patient:
A. Consult physician
B. Obtain WBC count
C. Obtain platelet count
D. All of the above.
Plummer – vinson syndrome:
A. Is due to folic acid deficiency
B. common in males
C. Not associated with oral premalignancy
D. Strong association with post-cricoid carcinoma
Chronic granulocytic leukemia is due to:
A. Chromosomal deletion
B. Chromosomal mutation
C. Chromosomal translocation
D. None of the above
Common oral change seen with nutritional anemia is:
A. Enlarged tongue
B. Atrophic glossitis
C. Generalized osteolysis
D. Focal marrow expansion
Christmas disease is due to deficiency of:
A. Hageman Factor
B. Platelets
C. Plasma thromboplastin antecedent
D. Plasma thromboplastin component
Clinical features of infectious mononucleosis:
A. Glandular involvement
B. Febrile
C. Palatine Petechiae
D. All of the above
Leucocytopenia is seen in:
A. influenza
B. agranulocytosis
C. liver cirrhosis
D. All of the above
Which of the following is not associated with haemorrhage:
A. Ecchymosis
B. Petechiae
C. Melanosis
D. Purpura
Which of the following agents is of value in the postoperative care of the hemophilic patient?
A. Vitamin K
B. Monsel’s solution
C. Aminocaproic acid
D. Factor 8 cryoprecipitate
Hemophilia B is due to:
A. Factor VII deficiency
B. Factor IX deficiency
C. Platelet deficiency
D. it C deficiency
Which of the following disease is known as the Kissing disease:
A. Acquired immunodeficiency syndrome (AIDS)
B. Infection mononucleosis
C. Primary syphilis
D. Recurrent apthous stomatitis
Neurological symptoms and premature graying of hair is associated with:
A. Folic acid deficiency
B. Pernicious anaemia
C. Plummer-Vinson syndrome
D. Paterson-Kelly syndrome
Hair-on-end appearance in a skull roentgenogram is seen in:
A. Fibrous dysplasia
B. Thalassemia
C. Garre’s Osteomyelitis
D. Pagets disease
The oral findings in erythroblastosis fetalis include:
A. Dentinal dysplasia
B. Hypoplastic teeth
C. Pigmented teeth
D. All of the above
Commonest mode of inheritance of Von Willebrand’s disease is:
A. Codominant
B. Autosomal dominan
C. Autosomal recessive
D. X-Linked recessive
All the following are TRUE in Immune thrombocytopenic Purpura (ITP) EXCEPT:
A. Chronic ITP commonly occur in adult women
B. Associated with normal bleeding time
C. Prothrombin Time (PT) & Partial Thromboplastin Time (PTT) are normal
D. Increased megakaryocytes in bone marrow
The most reliable criteria in Gustafson’s method of identification is:
A. Cementum apposition
B. Transparency of root
C. Attrition
D. Root resorption
The most common coagulation disorders haemophilia A and von Willebrand’s disease are due to:
A. Factor IX deficiency
B. Vitamin K deficiency
C. Factor X deficiency
D. Factor VIII deficiency
Cooley’s anemia is also known as:
A. Erythroblastosis fetalis
B. Aplatic anemia
C. Thalassemia
D. Pernicious anemia
Erythroblastosis fetalis can be prevented if the mother is injected at parturition, with an antibody called:
A. Blocking antibody
B. Rh (D) immunoglobulin
C. Antilymphocyte globulin
D. Antithymocyte serum
A patient on warfarin sodium following myocardial infarction reports for an oral surgical procedure which one of the following laboratory tests should be preferred to ascertain the fitness:
A. Prothrombin time
B. Tourniquet time
C. Clotting time
D. Bleeding time
Aplastic anaemia is common with:
A. Chloramphenicol
B. Cephalosporin
C. Tetracycline
D. Penicillin
Megaloblastic anaemia occurs due to:
A. Iron deficiency
B. Folate deficiency
C. Vitamin C deficiency
D. Protein deficiency
Virus responsible for infectious mononucleosis is:
A. RNA paramyxo virus
B. Varicella zoster virus
C. Epstein Barr virus
D. Coxsackie virus A 16
Infectious mononucleosis has:
A. Multiple draining sinuses
B. Ulcers which bruise easily
C. Palatal perforation
D. Alveolar bone loss
Monospot test is used to diagnose:
A. Pernicious anemia
B. Sickle cell anemia
C. Infectious mononucleosis
D. Leukemia
All of the following statements about acute leukemia in children are true except:
A. It characteristically causes gross gingival swelling
B. It may be manifested by mucosal pallor
C. It can cause abvious prupura
D. It is usually of the lymphoblastic variety
Bleeding joints is a characteristic feature of:
A. Vit – C deficiency
B. Heamophilia
C. Vit – K deficiency
D. Thrombocytopenia
Hypopigmentation, gray streaks of hair, degranulation defect of neutrophils and neuropathy are seen in:
A. alukemic leukemia
B. chronic granulocytic leukemia
C. lazy leukocyte syndrome
D. Chediak higashi syndrome
A boy complains of bleeding gums, swollen, joints with hemorrhage into joints His paternal and maternal uncle complains of same problem It is due to deficiency of factor:
A. VIII
B. IX
C. X
D. VI
Petechial hemorrhage is seen in:
A. cyclic neutropenia
B. agranulocytosis
C. pernicious anemia
D. thrombocytopenic purpura
Bleeding time is prolonged in:
A. Haemophilia
B. Von Willebrand’s disease
C. Henoch Schenolein purpura
D. Telangiectasia
Necrotising ragged ulceration with no apparent inflammatory response is indicative of:
A. Leucocytosis
B. Polycythemia vera
C. Sickle cell anemia
D. Agranulocytosis
Pernicious anemia is:
A. insufficient production of red cells
B. Improper maturation of red cells
C. can be correct by tablets of folic acid alone
D. can be correct by iron supplement
Pinpoint hemorrhages of < 1cm diameter are known as:
A. Petechiae
B. Ecchymoses
C. Purpura
D. Pustules
Paul Bunnell test is positive in:
A. Infectious mononucleosis
B. Multiple myeloma
C. Malignant nerves
D. Rubella
To prevent excessive bleeding during surgery a patient with hemophilia A may be given:
A. Whole blood
B. Fresh frozen plasma
C. Factor VIII concentrate
D. Factor IX concentrate
Which of the following is seen in idiopathic thrombocytopenic purpura:
A. Thrombocytosis
B. Increased prothrombin time
C. Increased bleeding time
D. Increased clotting time
Which of the following is not a finding in classical hemophilia (hemophilia A):
A. Bleeding into soft tissues, muscles and joints
B. Decreased factor VIII
C. Increase prothrombin Time
D. Increase Partial thromboplastin Time
The red blood cells in beta thalassemia are typically:
A. Macrocytic and normochromic
B. Microcytic and Hypochromic
C. Normocytic and hypochromic
D. Normocytic and normochromic
Which of the following statements about idiopathic thrombocytopenic purpura are true EXCEPT:
A. It is associated with palatelet-specific auto-antibodies
B. It caused a prolonged bleeding time
C. It is often controlled by immunosuppressive treatment
D. It causes more prolonged hemorrhage than hemophilia